Fig. 1 · Structure
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DMBP
VPS41 Inhibitor
DMBP is a VPS41 inhibitor that targets late endosomal and autophagosomal fusion with lysosomes. This compound induces methuosis and effectively inhibits autophagy in cancer cells, demonstrating significant potential in cancer research. Notably, DMBP has shown efficacy in reducing metastasis in a mouse model of metastatic melanoma, making it a valuable tool for studying melanoma progression and treatment.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 133156-42-0 |
| Applications | VPS41 Inhibitor |
| Formula | C21H24O4 |
| Molecular Weight | 340.41 |
| SMILES | O=C(OC)C1=C(CCC2=CC=CC=C2)C=C(O)C(C/C=C(C)\C)=C1O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.