dMCL1-2

Name: dMCL1-2
Brand: Adooq Bioscience
SKU: A18378
Rating: 5 (288 reviews)

Catalog No.: A18378

MCL-1/PROTAC degrader

dMCL1-2 is a potent and selective degrader of myeloid cell leukemia 1 (MCL1) based on PROTAC, which binds to MCL1 with a KD of 30 nM. dMCL1-2 activats the cellular apoptosis machinery by degradation of MCL1.

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dMCL1-2 2351218-88-5 MCL-1/PROTAC degrader

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Grouped product items
Size	Price	Stock
5mg	$345.00	In stock
10mg	$645.00	In stock
50mg	$1,995.00	In stock
Bulk Size	Bulk Discount

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Data Sheet SDS

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Biological Activity

Description	dMCL1-2 is a potent and selective degrader of myeloid cell leukemia 1 (MCL1) based on PROTAC, which binds to MCL1 with a KD of 30 nM. dMCL1-2 activats the cellular apoptosis machinery by degradation of MCL1.

Product Information

Catalog Num	A18378
Formula	C61H66N10O12S
Molecular Weight	1163.3
CAS Number	2351218-88-5
SMILES	O=S(N(CC1)CCN1C(C=C2)=CC=C2OCC3=C(C4=C(N(CCN5CCN(C(COC6=CC=CC(C(N7C8C(NC(CC8)=O)=O)=O)=C6C7=O)=O)CC5)C(C(O)=O)=C9CCCOC%10=C(C=CC=C%11)C%11=CC=C%10)C9=CC=C4)C(C)=NN3C)(N(C)C)=O
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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