Fig. 1 · Structure
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DMeOB
mGluR5 Negative Allosteric Modulator
DMeOB (3,3'-Dimethoxybenzaldazine) is a negative allosteric modulator of the mGluR5 receptor, exhibiting an IC50 of 3 μM. This compound demonstrates reversible non-competitive inhibition of mGlu5-mediated signaling. DMeOB is instrumental for research into mGluR5-related pathways and may be utilized in studies focused on neurological disorders and psychiatric conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 40252-74-2 |
| Applications | mGluR5 Negative Allosteric Modulator |
| Formula | C16H16N2O2 |
| Molecular Weight | 268.31 |
| Synonyms | 3,3'-Dimethoxybenzaldazine |
| SMILES | COC1=CC(/C=N/N=C/C2=CC=CC(OC)=C2)=CC=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.