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DML3

DNA Demethylating Agent

DML3 is a potent DNA demethylating agent that functions as a 5-methylcytosine DNA glycosylase. It selectively recognizes and excises 5-methylcytosine (5-meC) from DNA via a base excision repair mechanism, thereby playing a critical role in modulating epigenetic modifications. This reagent is particularly valuable in research focused on plant epigenetic regulation and cancer biology, offering insights into the dynamics of DNA methylation and its implications for gene expression.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1230-77-9
Applications	DNA Demethylating Agent
Formula	C₁₈H₁₉NO₂
Molecular Weight	281.36
SMILES	O=C(C=CC1=CC=C(C=C1)N(C)C)C2=CC=C(OC)C=C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.