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DMOG is a cell permeable, competitive inhibitor of HIF-PH. It acts to stabilize HIF-1α expression at normal oxygen tensions in cultured cells, at concentrations between 0.1 and 1 mM.
Targets
| HIF prolyl hydroxylase | ||||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 57.1 mL | 285.49 mL | 570.97 mL |
| 0.5 mM | 11.42 mL | 57.1 mL | 114.19 mL |
| 1 mM | 5.71 mL | 28.55 mL | 57.1 mL |
| 5 mM | 1.14 mL | 5.71 mL | 11.42 mL |
*The above data is based on the productmolecular weight 175.14. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A13998 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 175.14 |
| Formula | C6H9NO5 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 89464-63-1 |
| Synonyms | Dimethyloxaloyl glycine |
| SMILES | COC(=O)CNC(=O)C(=O)OC |
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