DMOG

Catalog No.: A13998

HIF-PH inhibitor

DMOG

DMOG Chemical Structure

CAS NO. 89464-63-1

DMOG is a cell permeable, competitive inhibitor of HIF-PH. It acts to stabilize HIF-1α expression at normal oxygen tensions in cultured cells, at concentrations between 0.1 and 1 mM.

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100 mg
$110.00
200 mg
$190.00
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  • Hideaki Nakamura, .et al. Differentiated embryo chondrocyte plays a crucial role in DNA damage response via transcriptional regulation under hypoxic conditions, PLoS One, 2018, 13(2): e0192136 PMID: 29466367

Biological Activity

DMOG is a cell permeable, competitive inhibitor of HIF-PH. It acts to stabilize HIF-1α expression at normal oxygen tensions in cultured cells, at concentrations between 0.1 and 1 mM.
Targets
HIF prolyl hydroxylase
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 57.1 mL 285.49 mL 570.97 mL
0.5 mM 11.42 mL 57.1 mL 114.19 mL
1 mM 5.71 mL 28.55 mL 57.1 mL
5 mM 1.14 mL 5.71 mL 11.42 mL

*The above data is based on the productmolecular weight 175.14. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13998
Actions Inhibitor
M. Wt 175.14
Formula C6H9NO5
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 89464-63-1
Synonyms Dimethyloxaloyl glycine
SMILES COC(=O)CNC(=O)C(=O)OC

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