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DMT-2'-F-U

Nucleoside

DMT-2'-F-U (5'-O-Trityl-2'-deoxy-2'-fluorouridine) is a modified nucleoside featuring a DMT protecting group at the 5' end, which facilitates biochemical manipulation and stability. This compound serves as a fluorinated uridine analog, making it valuable for studies in RNA biology and nucleic acid research. Its unique structure and properties allow for applications in the synthesis of antisense oligonucleotides and RNA therapeutics, providing insight into nucleotide interactions and cellular processes.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2923-90-2
Applications	Nucleoside
Formula	C₂₈H₂₅FN₂O₅
Molecular Weight	488.51
Synonyms	5′-O-Trityl-2′-deoxy-2′-fluorouridine
SMILES	O[C@H]1[C@@H](F)[C@H](N2C(NC(C=C2)=O)=O)O[C@@H]1COC(C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.