Fig. 1 · Structure
Documents & Downloads
DMT-2'fluoro-da(bz) amidite
Intermediate
DMT-2'fluoro-da(bz) amidite is an essential intermediate in the synthesis of antisense oligonucleotides, providing significant nuclease resistance and enhanced RNA binding affinity. Its unique structure supports the maintenance of base-pair specificity, making it a valuable reagent for research in molecular genetics and therapeutic development. This compound is particularly useful in studies focused on gene regulation and RNA-targeted therapies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 136834-22-5 |
| Applications | Intermediate |
| Formula | C47H51FN7O7P |
| Molecular Weight | 875.92 |
| SMILES | COC(C=C1)=CC=C1C(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)OC[C@@H]4[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](F)[C@H](N5C6=NC=NC(NC(C7=CC=CC=C7)=O)=C6N=C5)O4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.