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DMT-2'-O-Methyladenosine phosphoramidite

Catalog No.: A38700
For Oligonucleotide Synthesis
DMT-2'-O-Methyladenosine phosphoramidite is a phosphoramidite monomer utilized in oligonucleotide synthesis. This compound facilitates the incorporation of 2'-O-methyladenosine modifications into RNA sequences, which can enhance stability and reduce immunogenicity. Its primary applications include the development of modified oligonucleotides for therapeutic and diagnostic research.
DMT-2'-O-Methyladenosine phosphoramidite 138906-75-9 For Oligonucleotide Synthesis
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
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Nature volume 574, pages268-272 (2019)
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Nature volume 551, pages639-643 (2017)
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Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDMT-2'-O-Methyladenosine phosphoramidite is a phosphoramidite monomer utilized in oligonucleotide synthesis. This compound facilitates the incorporation of 2'-O-methyladenosine modifications into RNA sequences, which can enhance stability and reduce immunogenicity. Its primary applications include the development of modified oligonucleotides for therapeutic and diagnostic research.
Product Information
Catalog NumA38700
FormulaC41H50N7O7P
Molecular Weight783.85
CAS Number138906-75-9
SMILESCOC(C=C1)=CC=C1C(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)OC[C@@H]4[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](OC)[C@H](N5C6=NC=NC(N)=C6N=C5)O4
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This equation is commonly abbreviated as: C1V1 = C2V2

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