Fig. 1 · Structure

Documents & Downloads

DMT-2'-O-Methylguanosine phosphoramidite

For Oligonucleotide Synthesis

DMT-2'-O-Methylguanosine phosphoramidite is a phosphoramidite monomer designed for oligonucleotide synthesis. It serves as a key building block for the incorporation of modified guanosine residues in RNA and DNA constructs. This reagent enables enhanced stability and improved binding affinity in nucleic acid applications, making it suitable for use in various research areas, including gene therapy and antisense oligonucleotide development.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 1159683-24-5
Applications For Oligonucleotide Synthesis
Formula C41H50N7O8P
Molecular Weight 799.85
SMILES
COC(C=C1)=CC=C1C(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)OC[C@@H]4[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](OC)[C@H](N5C(N=C(N)NC6=O)=C6N=C5)O4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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