Fig. 1 · Structure
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DMT-2'O-MOE-rG(ib) Phosphoramidite
Oligonucleotide Synthesis Intermediate
DMT-2'O-MOE-rG(ib) Phosphoramidite is a cyanoethyl-protected nucleoside phosphoramidite designed for use as an intermediate in oligonucleotide synthesis. This derivative of guanosine facilitates the stereochemical synthesis of phosphorothioate oligonucleotides, enabling specific modifications crucial for various biochemical applications. Its unique structure allows for enhanced stability and reactivity in synthetic processes, making it an essential reagent for researchers in nucleic acid chemistry.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 251647-55-9 |
| Applications | Oligonucleotide Synthesis Intermediate |
| Formula | C47H60N7O10P |
| Molecular Weight | 913.99 |
| SMILES | COCCO[C@@H]1[C@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](COC(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)C4=CC=C(OC)C=C4)O[C@H]1N5C=NC6=C5N=C(NC6=O)NC(C(C)C)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.