Fig. 1 · Structure
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DMT-2'-OMe-D-Ribitol phosphoramidite
Phosphate Amide Monomer
DMT-2'-OMe-D-Ribitol phosphoramidite is a phosphate amide monomer used in the synthesis of oligonucleotides. This compound enables the introduction of abasic sites, specifically the abasic group Y34, into oligonucleotide sequences. Its utility in nucleic acid research facilitates studies on DNA structure and function, as well as applications in therapeutic development and diagnostics.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1470023-72-3 |
| Applications | Phosphate Amide Monomer |
| Formula | C36H47N2O7P |
| Molecular Weight | 650.74 |
| SMILES | COC(C=C1)=CC=C1C(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)OC[C@@H]4[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](OC)CO4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.