Fig. 1 · Structure
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DMT-locMeC(bz) phosphoramidite
For Oligonucleotide Synthesis
DMT-locMeC(bz) phosphoramidite is a key building block for oligonucleotide synthesis, specifically designed to enhance the incorporation of modified nucleosides. This reagent facilitates the formation of phosphodiester bonds, contributing to the structural diversity of oligonucleotides. Its application is critical in the development of research tools such as antisense oligonucleotides and RNA interference technologies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 206055-82-5 |
| Applications | For Oligonucleotide Synthesis |
| Formula | C48H54N5O9P |
| Molecular Weight | 875.94 |
| SMILES | COC1=CC=C(C(OC[C@]23CO[C@]([C@H](N4C=C(C)C(NC(C5=CC=CC=C5)=O)=NC4=O)O3)([H])[C@@H]2OP(OCCC#N)N(C(C)C)C(C)C)(C6=CC=C(OC)C=C6)C7=CC=CC=C7)C=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.