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DNA Gyrase-IN-6

GyrB/ParE inhibitor

DNA Gyrase-IN-6 is a dual inhibitor targeting GyrB and ParE, essential components of bacterial DNA gyrase and topoisomerase IV. This compound demonstrates significant antibacterial activity against both Gram-positive and Gram-negative bacterial strains. Its favorable solubility and plasma protein binding enhance its potential for research applications in the study of bacterial resistance mechanisms and the development of novel antimicrobial therapies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3034242-80-0
Applications	GyrB/ParE inhibitor
Formula	C₁₈H₁₆Cl₂N₄O₄S
Molecular Weight	455.32
SMILES	CC1=C(C(Cl)=C(N1)C(NC2=NC3=C(S2)C=C(C=C3N4CCOCC4)C(O)=O)=O)Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.