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DNA ligase-IN-1

LigA Inhibitor

DNA ligase-IN-1 is an inhibitor of bacterial NAD+-dependent DNA ligase, specifically targeting LigA. This compound demonstrates potent antibacterial activity by effectively inhibiting the growth of Staphylococcus aureus in vitro. Its application extends to the study of bacterial DNA repair mechanisms and the development of antibacterial agents.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	68302-07-8
Applications	LigA Inhibitor
Formula	C₁₃H₉N₃O₃
Molecular Weight	255.23
SMILES	O=C(C1=CC2=C(OC3=C(C2=O)C=CC=C3)N=C1N)N

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.