DNA-PK-IN-12 is a potent DNA-PK inhibitor, displaying an IC50 of 0.1 nM. This compound effectively inhibits cell growth and Hct116 cell colony formation with an IC50 of 33.28 μM. Additionally, DNA-PK-IN-12 demonstrates significant antitumor activity in vivo, making it a valuable reagent for cancer research and therapeutic studies.
DNA-PK-IN-12 is a potent DNA-PK inhibitor, displaying an IC50 of 0.1 nM. This compound effectively inhibits cell growth and Hct116 cell colony formation with an IC50 of 33.28 μM. Additionally, DNA-PK-IN-12 demonstrates significant antitumor activity in vivo, making it a valuable reagent for cancer research and therapeutic studies.
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