Fig. 1 · Structure
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Dofetilide-d4
Class III Antiarrhythmic Agent
Dofetilide-d4 is a deuterium-labeled derivative of Dofetilide, a class III antiarrhythmic agent that primarily targets potassium ion channels. It is utilized in research to investigate cardiac arrhythmias and the mechanisms of ion channel modulation. The incorporation of deuterium allows for enhanced metabolic stability and tracking in biological systems, making it valuable for pharmacokinetic studies and the development of antiarrhythmic therapies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1189700-56-8 |
| Applications | Class III Antiarrhythmic Agent |
| Formula | C19H23D4N3O5S2 |
| Molecular Weight | 445.59 |
| Synonyms | UK 68789 d4 |
| SMILES | CS(=O)(NC1=CC=C(CCN(C)C([2H])([2H])C([2H])([2H])OC2=CC=C(NS(=O)(C)=O)C=C2)C=C1)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.