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|Storage||at -20°C 3 years Powder|
|Domperidone blocks the action of dopamine. It has strong affinities for the D2 and D3 dopamine receptors, which are found in the chemoreceptor trigger zone, located just outside the blood brain barrier, which, among others, regulates nausea and vomiting (area postrema on the floor of the fourth ventricle and rhomboid fossa).|
|Solubility (25°C)*||In vitro||DMSO||48 mg/mL (112.69 mM)|
|Water||<1 mg/mL (<1 mM)|
|Ethanol||1 mg/mL (2.34 mM)|
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||23.48 mL||117.4 mL||234.79mL|
|0.5 mM||4.7 mL||23.48 mL||46.96 mL|
|1 mM||2.35 mL||11.74 mL||23.48 mL|
|5 mM||0.47 mL||2.35 mL||4.7 mL|
*The above data is based on the productmolecular weight 425.91. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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