Fig. 1 · Structure

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Dopamine D2 receptor antagonist-1

Dopamine Receptor Antagonist

Dopamine D2 receptor antagonist-1 is a negative allosteric modulator of the dopamine D2 receptor (D2R) that exhibits sub-micromolar affinity. This compound is utilized in research studying dopaminergic signaling pathways and provides insights into neurological disorders associated with D2R dysfunction. Its role in modulating receptor activity makes it a valuable tool for exploring pharmacological interventions in the central nervous system.

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Specifications

Manufacturer Adooq Bioscience
Actions Modulator
CAS Number 1055411-77-2
Applications Dopamine Receptor Antagonist
Formula C14H17N3S
Molecular Weight 259.37
SMILES
C12=NC=NC(NC3CCC3)=C1C4=C(CCCC4)S2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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