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Dopamine D3 receptor antagonist-1

Dopamine Receptor Antagonist

Dopamine D3 receptor antagonist-1 is a selective antagonist of the dopamine D3 receptor, exhibiting a binding affinity with a Ki value of 1.58 nM. This compound is of particular interest in the study of central nervous system disorders, as it may play a role in modulating dopaminergic signaling pathways. Its unique bitopic ligand properties suggest applications in researching both psychiatric and neurodegenerative conditions, providing valuable insights into therapeutic interventions.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Antagonist
CAS Number	3052236-36-6
Applications	Dopamine Receptor Antagonist
Formula	C₃₁H₃₅Cl₂N₃O₃
Molecular Weight	568.53
SMILES	O=C(NCCCCN1CCN(C2=CC=CC(Cl)=C2Cl)CC1)C3OCC(C4=CC=CC=C4)(C5=CC=CC=C5)OC3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.