Fig. 1 · Structure

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Dopamine D3 receptor ligand-1

Dopamine D3 receptor ligand

Dopamine D3 receptor ligand-1 is a potent and selective ligand for the dopamine D3 receptor, exhibiting a high affinity with a Ki value of 8 nM. This compound demonstrates an impressive 89-fold selectivity for the D3 receptor over the D2 receptor (D2 Ki = 715 nM). Its specificity makes it a valuable tool for investigating the D3 receptor's role in various neurobiological processes and for drug discovery efforts targeting dopamine-related disorders.

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Specifications

Manufacturer Adooq Bioscience
Actions Ligand / Binder
CAS Number 2882828-93-3
Applications Dopamine D3 receptor ligand
Formula C27H29N5O
Molecular Weight 439.55
SMILES
N#CC1=C(C=CC=C1)N2CCN(CC2)CCCCC(NC3=CC=C(C=C3)C4=NC=CC=C4)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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