Fig. 1 · Structure

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Dopamine D3 receptor ligand-2

D3 Receptor Ligand

Dopamine D3 receptor ligand-2 is a selective antagonist targeting the D3 dopamine receptor, exhibiting a Ki of 11.4 nM. This compound demonstrates high selectivity, showing minimal affinity for the D2 receptor with a Ki of 1228 nM. It is valuable for studies related to neurological disorders, addiction research, and the exploration of dopaminergic pathways.

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Specifications

Manufacturer Adooq Bioscience
Actions Antagonist
CAS Number 2882828-95-5
Applications D3 Receptor Ligand
Formula C27H29N5O
Molecular Weight 439.55
SMILES
N#CC1=CC(N2CCN(CC2)CCCCC(NC3=CC=C(C=C3)C4=NC=CC=C4)=O)=CC=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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