Fig. 1 · Structure
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Dopamine D3 receptor ligand-5
D3 Receptor Ligand
Dopamine D3 Receptor Ligand-5 is a selective ligand for the dopamine D3 receptor, exhibiting a Ki value of 0.14 nM, indicating high affinity. Additionally, it also demonstrates significant interaction with the D2 receptor, possessing a Ki value of 2.85 nM. This compound is primarily utilized in neurological research to investigate dopamine signaling pathways and their implications in neuropsychiatric disorders. Its specificity for the D3 receptor makes it a valuable tool for studies on receptor pharmacology and therapeutic development.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Ligand / Binder |
| CAS Number | 2899250-94-1 |
| Applications | D3 Receptor Ligand |
| Formula | C22H33Cl2N3O2 |
| Molecular Weight | 442.42 |
| SMILES | ClC1=C(C=CC=C1Cl)N2CCN(CC2)CC[C@@H]3CC[C@H](CC3)NC(CCOC)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.