Fig. 1 · Structure
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Dopamine D4 receptor antagonist-1
DRD4 Antagonist
Dopamine D4 receptor antagonist-1 is a selective antagonist for the dopamine D4 receptor (DRD4), exhibiting a Ki of 9.0 nM for the Hd4.2 cell line. This compound is valuable for research into the pathophysiology of schizophrenia, providing insights into dopaminergic signaling pathways and potential therapeutic interventions. Its specificity and potency make it a useful tool for studying DRD4-related biological processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 444724-92-9 |
| Applications | DRD4 Antagonist |
| Formula | C18H19ClN4 |
| Molecular Weight | 326.82 |
| SMILES | ClC1=CC(N2CCN(CC2)CC3=NC4=C(N3)C=CC=C4)=CC=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.