Fig. 1 · Structure
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Dopamine D4 receptor ligand 2
Dopamine D4 Ligand
Dopamine D4 receptor ligand 2 is a selective ligand targeting the dopamine D4 receptor, exhibiting a potent inhibitory effect with an IC50 of 0.057 nM. In contrast, the compound demonstrates much lower affinity for D2 (>1000 nM), 5-HT1A (220 nM), and α1 (270 nM) receptors. This selectivity positions it as a valuable tool for studies investigating the role of dopamine D4 in neuropharmacology and related research areas.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Ligand / Binder |
| CAS Number | 219125-63-0 |
| Applications | Dopamine D4 Ligand |
| Formula | C20H24ClN3O2 |
| Molecular Weight | 373.88 |
| SMILES | O=C(NCCN1CCN(C2=CC=C(Cl)C=C2)CC1)C3=CC=CC(OC)=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.