Fig. 1 · Structure
Documents & Downloads
DORA-22
Dual Orexinergic Receptor Antagonist
DORA-22 is a dual orexinergic receptor antagonist that targets orexin receptors OX1 and OX2, playing a critical role in regulating arousal, sleep, and appetite. It effectively alleviates sleep disruption and addresses memory impairment associated with sleep disorders. DORA-22 is useful for research applications related to insomnia and other sleep-related conditions.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 1088991-95-0 |
| Applications | Dual Orexinergic Receptor Antagonist |
| Formula | C23H22F2N4O2 |
| Molecular Weight | 424.44 |
| SMILES | FC1=CC(C(N2C[C@H](COC3=NC=C(F)C=C3)CC[C@H]2C)=O)=C(C4=NC=CC=N4)C=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.