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Doranidazole

Radiosensitizer

Doranidazole is a potent radiosensitizer that targets hypoxic tumor cells. It has been shown to significantly enhance radiation-induced growth delay in SCCVII tumors, especially when administered intravenously prior to irradiation. The efficacy of Doranidazole is closely linked to the oxygenation status of the tumors, making it a valuable reagent for studying lymphoma and hypoxic pancreatic tumors in preclinical research settings.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	149838-23-3
Applications	Radiosensitizer
Formula	C₈H₁₃N₃O₆
Molecular Weight	247.21
Synonyms	PR 350; RP 343
SMILES	OC[C@H](O)[C@@H](CO)OCN1C([N+]([O-])=O)=NC=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.