Fig. 1 · Structure
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Dorzolamide
Carbonic Anhydrase II Inhibitor
Dorzolamide is a potent inhibitor of carbonic anhydrase II, exhibiting an IC50 of 0.18 nM for red blood cell CA-II and 600 nM for CA-I. This compound is known for its therapeutic applications in reducing intraocular pressure and has demonstrated potential anti-tumor activity. It is a valuable reagent for research in cancer biology and ocular studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 120279-96-1 |
| Applications | Carbonic Anhydrase II Inhibitor |
| Formula | C10H16N2O4S3 |
| Molecular Weight | 324.44 |
| Synonyms | L671152; MK507 |
| SMILES | O=S(C(S1)=CC2=C1S([C@@H](C)C[C@@H]2NCC)(=O)=O)(N)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
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| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.