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DOSPA (hydrochlorid)

Cationic lipid

DOSPA hydrochloride is a cationic lipid primarily used in the formulation of lipid nanoparticles (LNPs) for mRNA vaccine applications. Its ability to facilitate cellular uptake of nucleotides makes it a crucial component in the development of effective mRNA-based therapies, including COVID-19 vaccines. Researchers utilize DOSPA hydrochloride to enhance the stability and delivery efficiency of genetic material in various therapeutic contexts.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	913194-16-8
Applications	Cationic lipid
Formula	C₅₄H₁₁₅Cl₅N₆O₃
Molecular Weight	1073.79
SMILES	CCCCCCCC/C=C\CCCCCCCCOCC(OCCCCCCCC/C=C\CCCCCCCC)C[N+](C)(C)CCNC([C@@H](NCCCN)CCCNCCCN)=O.[Cl-].Cl.Cl.Cl.Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.