DOTA-C1-FAP-2286

Catalog No.: A64634
FAP Targeting Radioligand
DOTA-C1-FAP-2286 is a cysteic acid-modified radioligand that specifically targets fibroblast activation protein (FAP). With an IC50 of 127.64 nM, it binds competitively to FAP-expressing cells, allowing for targeted accumulation and expedited renal clearance. This compound is suitable for use as a PET/CT tracer in cancer research and can aid in the imaging of tumors with high FAP expression.
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5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDOTA-C1-FAP-2286 is a cysteic acid-modified radioligand that specifically targets fibroblast activation protein (FAP). With an IC50 of 127.64 nM, it binds competitively to FAP-expressing cells, allowing for targeted accumulation and expedited renal clearance. This compound is suitable for use as a PET/CT tracer in cancer research and can aid in the imaging of tumors with high FAP expression.
Product Information
Catalog NumA64634
FormulaC73H109N15O26S5
Molecular Weight1773.06
CAS Number3107530-08-2
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