Fig. 1 · Structure

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DOTA-Tyr-Lys-DOTA

Hapten

DOTA-Tyr-Lys-DOTA is a DOTA-based small molecule hapten designed for enhanced targeting in radioimmunotherapy applications. It demonstrates rapid clearance and minimal whole-body retention, making it suitable for studies involving pretargeted radioimmunotherapy. This compound facilitates the precise delivery of radiolabeled agents to tumor sites, thereby improving therapeutic efficacy while minimizing off-target effects in biological research.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2757339-62-9
Applications Hapten
Formula C47H75N11O18
Molecular Weight 1082.16
SMILES
O=C(N[C@H](C(O)=O)CCCCNC(CN(CCN(CC1)CC(O)=O)CCN(CCN1CC(O)=O)CC(O)=O)=O)[C@@H](NC(CN(CCN(CC2)CC(O)=O)CCN(CCN2CC(O)=O)CC(O)=O)=O)CC(C=C3)=CC=C3O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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