Fig. 1 · Structure
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DOTAP chloride
Cationic Lipid
DOTAP chloride is a cationic lipid primarily utilized for the transfection of DNA, including plasmids and bacmids, as well as modified nucleic acids such as antisense oligonucleotides. Its efficacy in facilitating both transient and stable transfection makes it a valuable tool in molecular biology research. The unique properties of DOTAP chloride allow for successful nucleic acid delivery without the requirement for helper lipids, supporting various applications in gene delivery and RNA research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 132172-61-3 |
| Applications | Cationic Lipid |
| Formula | C42H80ClNO4 |
| Molecular Weight | 698.54 |
| Synonyms | 1,2-Dioleoyl-3-trimethylammonium-propane chloride |
| SMILES | CCCCCCCC/C=C\CCCCCCCC(OCC(OC(CCCCCCC/C=C\CCCCCCCC)=O)C[N+](C)(C)C)=O.[Cl-] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.