Fig. 1 · Structure

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Dotriacolide

β-actamase Inhibitor

Dotriacolide is a potent β-lactamase inhibitor that specifically targets penicillinase and cephalosporinase. It demonstrates significant inhibitory activity with ID50 values of 0.61 μg/mL and 0.15 μg/mL, respectively. This compound is valuable for studies related to infectious diseases, providing insights into overcoming antibiotic resistance mechanisms.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 80994-06-5
Applications β-actamase Inhibitor
Formula C40H76O18S4
Molecular Weight 973.28
SMILES
O=C1OC(CC(CCCCCCCCCCCC(CC(CCCCCCCCCCC/C=C/1)OS(=O)(O)=O)OS(=O)(O)=O)OS(=O)(O)=O)CCCCCCCC(C)OS(=O)(O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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