Dovitinib-d8 is a deuterated form of Dovitinib, a multi-targeted tyrosine kinase inhibitor. Dovitinib exhibits potent inhibitory activity against various kinases, including FLT3, c-Kit, FGFR1, VEGFR1, and PDGFR, with IC50 values ranging from 1 to 210 nM. This stable isotope-labeled reagent is particularly valuable in pharmacokinetic studies, enabling researchers to investigate drug metabolism and distribution in biological systems.
Dovitinib-d8 is a deuterated form of Dovitinib, a multi-targeted tyrosine kinase inhibitor. Dovitinib exhibits potent inhibitory activity against various kinases, including FLT3, c-Kit, FGFR1, VEGFR1, and PDGFR, with IC50 values ranging from 1 to 210 nM. This stable isotope-labeled reagent is particularly valuable in pharmacokinetic studies, enabling researchers to investigate drug metabolism and distribution in biological systems.
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