Fig. 1 · Structure
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Dovitinib-RIBOTAC
RNA RIBOTAC Degrader
Dovitinib-RIBOTAC is an RNA-targeting RIBOTAC degrader that specifically binds to and facilitates the degradation of pre-miR-21. This compound exhibits significant anti-tumor activity and inhibits metastasis in breast cancer models. It serves as a valuable tool for studying the role of miR-21 in cancer biology and therapeutic development.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Degrader |
| CAS Number | 2759351-68-1 |
| Applications | RNA RIBOTAC Degrader |
| Formula | C51H56FN9O10S |
| Molecular Weight | 1006.11 |
| SMILES | O=C1C(C2=NC3=CC(N4CCN(CCNC(NCCOCCOCCOCCOC5=C(O)C=C(/C=C6C(C(C(OCC)=O)=C(NC7=CC=CC=C7)S/6)=O)C=C5)=O)CC4)=CC=C3N2)=C(N)C8=C(C=CC=C8F)N1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.