Fig. 1 · Structure
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Dox-btn2
Biotin Labeled Doxorubicin
Dox-btn2 is a biotin-labeled derivative of Doxorubicin that incorporates a biotin tag at the 3'-NH2 position. This modification allows for enhanced cellular imaging applications, facilitating the study of drug localization and uptake. While traditional Doxorubicin primarily accumulates in the nucleus, Dox-btn2 predominantly localizes in the cytoplasm, providing unique insights into its biological behavior and mechanisms of action in cancer research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 3026061-31-1 |
| Applications | Biotin Labeled Doxorubicin |
| Formula | C48H64N4O18S |
| Molecular Weight | 1017.10 |
| Synonyms | Biotin Labeled Doxorubicin |
| SMILES | O=C1C2=C(O)C3=C([C@H](C[C@](C(CO)=O)(C3)O)O[C@H]4C[C@H](NC(CCOCCOCCOCCOCCNC(CCCC[C@H]5[C@@]6([H])NC(N[C@]6(CS5)[H])=O)=O)=O)[C@H](O)[C@H](C)O4)C(O)=C2C(C7=C1C=CC=C7OC)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.