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Doxorubamine

Doxorubicin Derivative

Doxorubamine is a derivative of Doxorubicin that primarily targets cancer cells by intercalating into DNA and inhibiting topoisomerase II. This compound demonstrates potent cytotoxicity against agent-sensitive ovarian cancer cells, making it a valuable tool in cancer research. Its reduced susceptibility as a substrate for P-glycoprotein enhances its effectiveness in overcoming multidrug resistance. Doxorubamine is essential for studies focusing on chemotherapy and mechanisms of drug resistance in oncology.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	760899-08-9
Applications	Doxorubicin Derivative
Formula	C₂₇H₃₀N₂O₁₀
Molecular Weight	542.53
SMILES	COC1=C(C(C(C(O)=C([C@@H](O[C@@H]2O[C@@H](C)[C@H](N)[C@@H](N)C2)C[C@](O)(C(CO)=O)C3)C3=C4O)=C4C5=O)=O)C5=CC=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.