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DQ661

PPT1 Inhibitor

DQ661 is a potent PPT1 inhibitor that functions as a dimeric quinacrine autophagy inhibitor. It effectively reduces mTORC1 activity and lowers the protein expression levels of phosphorylated S6K (T389) and S6 (S240-244). DQ661 demonstrates significant anticancer activity, making it a valuable tool for research into autophagy and related cancer pathways.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2027551-01-3
Applications	PPT1 Inhibitor
Formula	C₄₁H₄₇Cl₂N₅O₂
Molecular Weight	712.75
SMILES	ClC(C=CC1=C2NCCCCCCN(CCCCCCNC3=C4C=CC(Cl)=CC4=NC5=C3C=C(OC)C=C5)C)=CC1=NC6=C2C=C(OC)C=C6

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.