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Biological Activity
DRAK2-IN-1, compound 16, is a potent, selective and ATP-competitive DRAK2 inhibitor with IC50and Kivalues of 3 nM and 0.26 nM, respectively. DRAK2-IN-1 also has inbitory effect on DRAK1 (IC50=51 nM).
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.57 mL | 132.83 mL | 265.67 mL |
| 0.5 mM | 5.31 mL | 26.57 mL | 53.13 mL |
| 1 mM | 2.66 mL | 13.28 mL | 26.57 mL |
| 5 mM | 0.53 mL | 2.66 mL | 5.31 mL |
*The above data is based on the productmolecular weight 376.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A18433 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 871837-60-4 |
| Formula | C21H20N4O3 |
| M. Wt | 376.41 |
| Purity | >98% |
| SMILES | CCCCC(NC1=CC2=C(NC(/C2=C3NC4=C(C=CC=C4)C\3=N\O)=O)C=C1)=O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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