Fig. 1 · Structure
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DRI-C21041
CD40/CD40L Interaction Inhibitor
DRI-C21041 is a potent inhibitor of the CD40/CD40L interaction, exhibiting an IC50 value of 0.31 μM. By disrupting this key costimulatory pathway, DRI-C21041 effectively modulates immune responses, particularly those triggered by alloantigens. This compound is valuable for research applications focused on immunology, autoimmunity, and transplant biology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2101765-78-8 |
| Applications | CD40/CD40L Interaction Inhibitor |
| Formula | C30H21N3O7S |
| Molecular Weight | 567.57 |
| SMILES | O=S(C1=C2C(NC(C3=CC=C(C4=CC=C(NC(C5=CC=C([N+]([O-])=O)C=C5)=O)C=C4)C=C3)=O)=CC=CC2=CC=C1)(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.