Fig. 1 · Structure
Documents & Downloads
Drisapersen
Antisense Oligonucleotide
Drisapersen is an antisense oligonucleotide designed to promote exon 51 skipping in dystrophin pre-mRNA splicing. This mechanism facilitates the production of partially functional dystrophin, offering a potential therapeutic approach for patients with Duchenne muscular dystrophy (DMD) harboring specific amenable mutations. Its biological activity underscores its role in advancing research for targeted genetic therapies in muscle degeneration disorders.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1251830-50-8 |
| Applications | Antisense Oligonucleotide |
| Molecular Weight | 6978.00 |
| Synonyms | Kyndrisa; GSK2402968A; PRO051 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.