Fig. 1 · Structure

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DRP1 Allosteric-IN-1

DRP1 Allosteric Inhibitor

DRP1 Allosteric-IN-1 is an allosteric inhibitor of dynamin-related protein 1 (DRP1), demonstrating an IC50 of 3.6 μM for disrupting the DRP1:MiD49 protein-protein interaction. This compound serves as a valuable tool for investigating mitochondrial division disorders and associated pathologies. Its application in biochemical research can enhance the understanding of the role of mitochondrial dynamics in diverse diseases.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 1359386-11-0
Applications DRP1 Allosteric Inhibitor
Formula C21H22N2O2
Molecular Weight 334.41
SMILES
O=C(C(C)C)NC1=CC2=C(N=C(C3=CC=CC=C3)C=C2OCC)C=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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