Fig. 1 · Structure
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Drp1-IN-1
Drp1 Inhibitor
Drp1-IN-1 is a selective inhibitor of dynamin-related protein 1 (Drp1), exhibiting an IC50 of 0.91 μM. This compound interferes with Drp1's regulatory role in mitochondrial dynamics, promoting mitochondrial fusion and potentially mitigating cellular stress responses. Drp1-IN-1 is useful in research focused on mitochondrial function, neurodegenerative diseases, and other conditions where oxidative stress plays a critical role.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2247733-08-8 |
| Applications | Drp1 Inhibitor |
| Formula | C22H24N8OS |
| Molecular Weight | 448.54 |
| SMILES | O=C(C1=CC(C)=CN1CC2=CSC(N3CCCCC3)=N2)NC4=CC=C(C5=NN=NN5)C=C4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.