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DS1

Catalog No.: A66943
GABAA Agonist
DS1 is a potent agonist of the GABAA receptor, enhancing its activity. This compound stimulates serum response element (SRE) and cAMP response element (CRE) promoters, leading to increased expression of luteinizing hormone beta (LHbeta) and follicle-stimulating hormone beta (FSHbeta) genes. DS1 is valuable for research applications focused on the modulation of GABAA receptor activity and its effects on hormone regulation.
DS1 372497-52-4 GABAA Agonist
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
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Research use only. We do not sell to patients.
Data Sheet SDS

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDS1 is a potent agonist of the GABAA receptor, enhancing its activity. This compound stimulates serum response element (SRE) and cAMP response element (CRE) promoters, leading to increased expression of luteinizing hormone beta (LHbeta) and follicle-stimulating hormone beta (FSHbeta) genes. DS1 is valuable for research applications focused on the modulation of GABAA receptor activity and its effects on hormone regulation.
Product Information
Catalog NumA66943
FormulaC18H10Br2ClN3OS
Molecular Weight511.62
CAS Number372497-52-4
SMILESO=C(NC1=C(C2=CC=CS2)N=C3C(Br)=CC(Br)=CN31)C4=CC=C(Cl)C=C4
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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Neuronal Signaling > GABA Receptors