Fig. 1 · Structure
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DS1
GABAA Agonist
DS1 is a potent agonist of the GABAA receptor, enhancing its activity. This compound stimulates serum response element (SRE) and cAMP response element (CRE) promoters, leading to increased expression of luteinizing hormone beta (LHbeta) and follicle-stimulating hormone beta (FSHbeta) genes. DS1 is valuable for research applications focused on the modulation of GABAA receptor activity and its effects on hormone regulation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 372497-52-4 |
| Applications | GABAA Agonist |
| Formula | C18H10Br2ClN3OS |
| Molecular Weight | 511.62 |
| SMILES | O=C(NC1=C(C2=CC=CS2)N=C3C(Br)=CC(Br)=CN31)C4=CC=C(Cl)C=C4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.