Fig. 1 · Structure
Documents & Downloads
DS17
Cyclin K Degrader
DS17 is a molecular glue that functions as a potent degrader of cyclin K, exhibiting an EC50 value of 13 nM. This compound is pivotal for cancer research due to its ability to modulate cell cycle dynamics and influence tumor progression. Researchers can utilize DS17 to investigate the therapeutic potential of targeting cyclin K in various malignancies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Degrader |
| CAS Number | 3068546-95-9 |
| Applications | Cyclin K Degrader |
| Formula | C20H24Cl2N8O |
| Molecular Weight | 463.36 |
| SMILES | CC(C)N(C=N1)C2=C1C(NCC3=NC(C=C(Cl)C(Cl)=C4)=C4N3)=NC(N[C@H](CC)CO)=N2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.