Fig. 1 · Structure
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DS2
δ-GABAA Receptor Positive Allosteric Modulator
DS2 is a selective positive allosteric modulator of the δ-GABAA receptor. This compound specifically enhances GABAergic responses mediated by the α4β3δ receptor while exhibiting minimal activity at α4β3γ2 and α1β3γ2 receptors. DS2 demonstrates significant analgesic properties and holds potential for research in sleep disorders, making it a valuable tool in neuropharmacology studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 374084-31-8 |
| Applications | δ-GABAA Receptor Positive Allosteric Modulator |
| Formula | C18H12ClN3OS |
| Molecular Weight | 353.83 |
| SMILES | O=C(NC1=C(C2=CC=CS2)N=C3C=CC=CN31)C4=CC=C(Cl)C=C4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.