Fig. 1 · Structure

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DS37571084

PTHR1 Antagonist

DS37571084 is a potent antagonist of the parathyroid hormone type 1 receptor (PTHR1), exhibiting an IC50 value of 0.17 μM. This compound is suitable for research applications focused on hyperparathyroidism, facilitating a deeper understanding of its underlying mechanisms and potential therapeutic interventions.

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Specifications

Manufacturer Adooq Bioscience
Actions Antagonist
CAS Number 2460353-87-9
Applications PTHR1 Antagonist
Formula C28H30Cl2N4O2
Molecular Weight 525.47
SMILES
O=C1N(C2=CC=C(NCCNC3CCOCC3)C=C2)C4=CC(Cl)=CC=C4C5=CC(Cl)=CN=C5C1(C)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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