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DS42450411

Hepcidin Production Inhibitor

DS42450411 is an orally active hepcidin production inhibitor that functions with an IC50 of 32 nM. This compound significantly reduces serum hepcidin levels in an acute inflammatory mouse model induced by IL-6. DS42450411 is valuable for research applications focused on iron homeostasis and the regulation of iron metabolism.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2247168-13-2
Applications	Hepcidin Production Inhibitor
Formula	C₂₂H₂₈N₄
Molecular Weight	348.48
SMILES	NC1=C2C(C)(C)CC3=CC(C([C@H]4CC[C@H](N)CC4)=C)=CC=C3C2=NC=N1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.