Fig. 1 · Structure
Documents & Downloads
DS68591889
PTDSS1 Inhibitor
DS68591889 is a selective and orally active inhibitor of phosphatidylserine synthase 1 (PTDSS1), demonstrating no inhibitory activity against PTDSS2. This compound induces phospholipid imbalance in various cancer cell lines and negatively regulates B cell receptor (BCR)-induced Ca2+ signaling, leading to apoptotic cell death. DS68591889 is applicable in cancer research, particularly in studies related to B cell lymphoma.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2488609-21-6 |
| Applications | PTDSS1 Inhibitor |
| Formula | C29H21F5N4O5 |
| Molecular Weight | 600.49 |
| SMILES | O=C1OC2=C(C3=NNC4=C3C(C5=CC=C(C=C5)OC6=CC=C(C(C)=C6)OC(F)(F)F)N(CC(F)(C)F)C4=O)C=CC=C2N1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.