Fig. 1 · Structure
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dTAG Targeting Ligand 1
Ligand for Target Protein for PROTAC
dTAG Targeting Ligand 1 is a ligand specifically designed for the targeted degradation of proteins using PROTAC technology. This compound facilitates the selective recruitment of E3 ligases to the target protein, promoting its ubiquitination and subsequent proteasomal degradation. dTAG Targeting Ligand 1 serves as a crucial tool in studies aimed at exploring protein function, validating drug targets, and developing novel therapeutic strategies through protein degradation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Ligand / Binder |
| CAS Number | 755039-56-6 |
| Applications | Ligand for Target Protein for PROTAC |
| Formula | C22H27N5O4 |
| Molecular Weight | 425.48 |
| SMILES | O=C1[C@@H](CC)N(C2CCCC2)C3=NC(NC4=C(OC)C=C(C=C4)C(O)=O)=NC=C3N1C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.