Duloxetine-d5 oxalate

Catalog No.: A79257
Stable Isotope
Duloxetine-d5 oxalate is a deuterium-labeled derivative of Duloxetine, primarily acting as a serotonin-norepinephrine reuptake inhibitor with a Ki of 4.6 nM. This stable isotope is useful in pharmacokinetic studies and investigations of drug metabolism. Its unique isotopic labeling enables precise tracking and quantification in biological assays, making it valuable for research in psychiatric disorders such as major depressive disorder and generalized anxiety disorder.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDuloxetine-d5 oxalate is a deuterium-labeled derivative of Duloxetine, primarily acting as a serotonin-norepinephrine reuptake inhibitor with a Ki of 4.6 nM. This stable isotope is useful in pharmacokinetic studies and investigations of drug metabolism. Its unique isotopic labeling enables precise tracking and quantification in biological assays, making it valuable for research in psychiatric disorders such as major depressive disorder and generalized anxiety disorder.
Product Information
Catalog NumA79257
FormulaC20H16D5NO5S
Molecular Weight392.48
CAS Number1276197-53-5
SMILESOC(C(O)=O)=O.[2H]C([2H])([2H])NC([2H])([2H])C[C@@H](C1=CC=CS1)OC2=CC=CC3=C2C=CC=C3
Synonyms(S)-Duloxetine-d5 oxalate; LY248686-d5 oxalate
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